Top Mekong River 50 Plus Trips & Packages In 2025/2026

Our 25 most popular Mekong River 50 Plus Trips & Packages trips. Compare tour itineraries from 12 tour companies. 23 reviews.

25 Trips match your criteria (1 - 22 shown)

Fascinating Vietnam, Cambodia & the Mekong River (Northbound)
Save this trip to your favorites or other list
4.7/5 Excellent
100+ reviews
River Cruise
Why we love them
They combine the assurance of working with a large cruise operator with the warmth and personal service of a boutique provider.
Lodging level
Standard - 3 star
Physical level
Very Easy
Trip pace
Flexible schedule

Visits

Cai Be, Chau Doc, Cu Chi Tunnels, Phnom Penh, Siem Reap, Vinh Long

Highlights

  • Welcome to Vietnam
  • Walking tour; visit the famous Rex Hotel for a drink, War Remnants Museum, and Ben Thanh Market; cooking class and lunch
  • Cu Chi Tunnels excursion
  • Onboard welcome reception
  • Visit a local workshop to see how rice paper, rice wine, and traditional candy are made in Vinh Long; interact with sampan-making and conical hat making families in Cu Lao Gieng
Show more

Themes

Cultural, 50 Plus, Small Ship Cruise

What travelers are saying

"The Avalon was so wonderful and all staff were very helpful in many ways, we couldn't fault the ship or staff. Would recommend Avalon river cruises. The rooms are lovely with great views."

Trip dates & details
Save this trip to your favorites or other list
More
Fascinating Vietnam, Cambodia & the Mekong River with Hanoi & Ha Long Bay (Southbound)
Save this trip to your favorites or other list
4.7/5 Excellent
100+ reviews
River Cruise
Why we love them
They combine the assurance of working with a large cruise operator with the warmth and personal service of a boutique provider.
Lodging level
Premium - 4 star
Physical level
Very Easy
Trip pace
Balanced schedule

Visits

Cai Be, Chau Doc, Cu Chi Tunnels, Ha Long Bay, Hanoi, Phnom Penh, Siem Reap, Vinh Long

Highlights

  • Welcome to Vietnam
  • Visit Ho Chi Minh’s mausoleum, One Pillar Pagoda, Ho Chi Minh Museum, and Temple of Literature; lunch at a local restaurant; take a cyclo ride through the Old Quarter; water puppets performance
  • Cruise on Ha Long Bay
  • Fly to Siem Reap
  • Visit Angkor Wat, Angkor Thom, and Bayon Temple; Apsara dance performance
Show more

Themes

Cultural, 50 Plus, Small Ship Cruise

What travelers are saying

"The Avalon was so wonderful and all staff were very helpful in many ways, we couldn't fault the ship or staff. Would recommend Avalon river cruises. The rooms are lovely with great views."

Trip dates & details
Save this trip to your favorites or other list
More
Fascinating Vietnam, Cambodia & the Mekong River with Hanoi, Ha Long Bay & Bangkok (Southbound)
Save this trip to your favorites or other list
4.7/5 Excellent
100+ reviews
River Cruise
Why we love them
They combine the assurance of working with a large cruise operator with the warmth and personal service of a boutique provider.
Lodging level
Standard - 3 star
Physical level
Very Easy
Trip pace
Balanced schedule

Visits

Cai Be, Chau Doc, Cu Chi Tunnels, Ha Long Bay, Hanoi, Phnom Penh, Siem Reap, Vinh Long

Highlights

  • Welcome to Vietnam
  • Visit Ho Chi Minh’s mausoleum, One Pillar Pagoda, Ho Chi Minh Museum, and Temple of Literature; lunch at a local restaurant; take a cyclo ride through the Old Quarter; water puppets performance
  • Cruise on Ha Long Bay
  • Fly to Siem Reap
  • Visit Angkor Wat, Angkor Thom, and Bayon Temple; Apsara dance performance
Show more

Themes

Cultural, 50 Plus, Small Ship Cruise

What travelers are saying

"The Avalon was so wonderful and all staff were very helpful in many ways, we couldn't fault the ship or staff. Would recommend Avalon river cruises. The rooms are lovely with great views."

Trip dates & details
Save this trip to your favorites or other list
More

Want a tailor-made trip instead?

Your trip, your way, planned by an expert:

  • You choose budget, destinations, activities, transport & lodging type
  • Expert designs the itinerary for you, and once approved, takes care of logistics
Design custom trip
Fascinating Vietnam, Cambodia & the Mekong River with Bangkok (Northbound)
Save this trip to your favorites or other list
4.7/5 Excellent
100+ reviews
River Cruise
Why we love them
They combine the assurance of working with a large cruise operator with the warmth and personal service of a boutique provider.
Lodging level
Standard - 3 star
Physical level
Very Easy
Trip pace
Flexible schedule

Visits

Cai Be, Chau Doc, Cu Chi Tunnels, Phnom Penh, Siem Reap, Vinh Long

Highlights

  • Welcome to Vietnam
  • Walking tour; visit the famous Rex Hotel for a drink, War Remnants Museum, and Ben Thanh Market; cooking class and lunch
  • Cu Chi Tunnels excursion
  • Onboard welcome reception
  • Visit a local workshop to see how rice paper, rice wine, and traditional candy are made in Vinh Long; interact with sampan-making and conical hat making families in Cu Lao Gieng
Show more

Themes

Cultural, 50 Plus, Small Ship Cruise

What travelers are saying

"The Avalon was so wonderful and all staff were very helpful in many ways, we couldn't fault the ship or staff. Would recommend Avalon river cruises. The rooms are lovely with great views."

Trip dates & details
Save this trip to your favorites or other list
More
Mekong Discovery (Northbound)
Save this trip to your favorites or other list
4.7/5 Excellent
100+ reviews
River Cruise
Why we love them
They combine the assurance of working with a large cruise operator with the warmth and personal service of a boutique provider.
Lodging level
Standard - 3 star
Physical level
Very Easy
Trip pace
Flexible schedule

Visits

Cai Be, Chau Doc, Cu Chi Tunnels, Phnom Penh, Siem Reap, Vinh Long

Highlights

  • Onboard welcome reception
  • Visit a local workshop to see how rice paper, rice wine, and traditional candy are made in Vinh Long; interact with sampan-making and conical hat making families in Cu Lao Gieng
  • Visit a local market and the religious sites at Sam Mountain in Chau Doc; walking tour of Long Khanh A with cotton-weaving demonstration
  • Sightseeing by private cyclo, including the Royal Palace, Silver Pagoda, and the National Museum; afternoon at leisure; show by children from a local orphanage
  • Visit the Tuol Sleng Genocide Museum and visit one of the Cambodian Killing Fields, or visit the lively central market
Show more

Themes

Cultural, 50 Plus, Small Ship Cruise

What travelers are saying

"The Avalon was so wonderful and all staff were very helpful in many ways, we couldn't fault the ship or staff. Would recommend Avalon river cruises. The rooms are lovely with great views."

Trip dates & details
Save this trip to your favorites or other list
More
Fascinating Vietnam, Cambodia & the Mekong River (Southbound)
Save this trip to your favorites or other list
4.7/5 Excellent
100+ reviews
River Cruise
Why we love them
They combine the assurance of working with a large cruise operator with the warmth and personal service of a boutique provider.
Lodging level
Standard - 3 star
Physical level
Very Easy
Trip pace
Flexible schedule

Visits

Cai Be, Chau Doc, Cu Chi Tunnels, Phnom Penh, Siem Reap, Vinh Long

Highlights

  • Welcome to Cambodia
  • Visit Angkor Wat, Angkor Thom, and Bayon Temple; Apsara dance performance
  • Visit Ta Prohm, Banteay Srei, and a noodle-making village
  • Fly to Phnom Penh; onboard welcome reception
  • Visit Wat Hanchey and partake in a traditional water blessing by local monks; walking tour in Angkor Ban with school visit
Show more

Themes

Cultural, 50 Plus, Small Ship Cruise

What travelers are saying

"The Avalon was so wonderful and all staff were very helpful in many ways, we couldn't fault the ship or staff. Would recommend Avalon river cruises. The rooms are lovely with great views."

Trip dates & details
Save this trip to your favorites or other list
More
Mekong Discovery (Southbound)
Save this trip to your favorites or other list
4.7/5 Excellent
100+ reviews
River Cruise
Why we love them
They combine the assurance of working with a large cruise operator with the warmth and personal service of a boutique provider.
Lodging level
Standard - 3 star
Physical level
Very Easy
Trip pace
Flexible schedule

Visits

Cai Be, Chau Doc, Cu Chi Tunnels, Phnom Penh, Siem Reap, Vinh Long

Highlights

  • Onboard welcome reception
  • Visit Wat Hanchey and partake in a traditional water blessing by local monks; walking tour in Angkor Ban with school visit
  • Ox-cart ride through the countryside and visit a local farmer’s home in Kampong Tralach; visit the silversmith village of Konpong Louang; visit the Tuol Sleng Museum and one of the Killing Fields in Phnom Penh, or visit the lively central market
  • Sightseeing by private cyclo, including the Royal Palace, Silver Pagoda, and the National Museum; show by children from local orphanage
  • Visit a local market and the religious sites at Sam Mountain in Chau Doc
Show more

Themes

Cultural, 50 Plus, Small Ship Cruise

What travelers are saying

"The Avalon was so wonderful and all staff were very helpful in many ways, we couldn't fault the ship or staff. Would recommend Avalon river cruises. The rooms are lovely with great views."

Trip dates & details
Save this trip to your favorites or other list
More
Fascinating Vietnam, Cambodia & the Mekong River with Hanoi, Ha Long Bay & Bangkok (Northbound)
Save this trip to your favorites or other list
4.7/5 Excellent
100+ reviews
River Cruise
Why we love them
They combine the assurance of working with a large cruise operator with the warmth and personal service of a boutique provider.
Lodging level
Standard - 3 star
Physical level
Very Easy
Trip pace
Flexible schedule

Visits

Cai Be, Chau Doc, Cu Chi Tunnels, Ha Long Bay, Hanoi, Phnom Penh, Siem Reap, Vinh Long

Highlights

  • Welcome to Vietnam
  • Visit Ho Chi Minh’s mausoleum, One Pillar Pagoda, Ho Chi Minh Museum, and Temple of Literature; lunch at local restaurant; take a cyclo ride through the Old Quarter; water puppets performance
  • Cruise on Ha Long Bay
  • Fly to Ho Chi Minh City
  • Walking tour; visit the famous Rex Hotel for a drink, War Remnants Museum, and Ben Thanh Market; cooking class and lunch
Show more

Themes

Cultural, 50 Plus, Small Ship Cruise

What travelers are saying

"The Avalon was so wonderful and all staff were very helpful in many ways, we couldn't fault the ship or staff. Would recommend Avalon river cruises. The rooms are lovely with great views."

Trip dates & details
Save this trip to your favorites or other list
More

Mekong River 50 Plus Trips & Packages Reviews

C

Caroline

Dec 2019

Written on

It was a great holiday.

Margaret and I would like to thank you for looking after us so well. It was a great holiday. The only thing we didn't like was the hotel where we had ...

S

Sherrill

Jun 2019

Written on

Great trip to Vietnam

Most of our trip was great. But one thing to say that there was supposed to be a Tai Chi lesson on the second day in Halong but that did not happen due to the rain. ...

T

Tina

Apr 2019

Written on

Good organization

I want to thank Realistic Asia so much for organizing this tour for us. ...

L

Leah

Mar 2019

Written on

5-star travel consultant

Thank you for everything I made for us. I always gave you a 5 star review for your sincere care and hard work. Do not feel bad about some hipcups that you managed to...

D

Deb

Oct 2018

Written on

Fantastic package from Realistic Asia

Just a quick email to say thank you for the fantastic package you put together for my family. We thoroughly enjoyed our stay in your beautiful country and the servic...

Write a Review
...

1

2

...
Sign in to reveal savings up to $700 per person!