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Top Mississippi River National Parks River Cruises & Packages In 2025/2026
Our 8 most popular Mississippi River National Parks River Cruises & Packages trips. Compare tour itineraries from 1 tour companies. 1 reviews.
8 Trips match your criteria (1 - 8 shown)
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River Cruise
Lodging level
Standard - 3 star
Physical level
Easy
Trip pace
Flexible schedule
Highlights
- Visit their popular gift shop which is known for their world-famous pralines.
- Enjoying the shade of the leafy canopy greet us on arrival and are our guides for the day.
- Visits to its gardens, historic homes, and museums
- See why this show is called "Becoming Jelly Roll."
- Enjoy the local flavors, like chicory coffee, sweet beignets, and famous New Orleans jazz music.
Themes
Cultural, Nature & Wildlife, National Parks
What travelers are saying
"The food and entertainment were exceptional! Such a professional staff providing top notch service! The entertainment was different each night throughout the entire trip. Also, the chef was a former Food Network Chopped Champion delivering a variety of delicious options, including desserts! Loved the cooking class for our day at sea! This is a new ship with beautiful cabins and common areas. There was plenty of space to meet with friends, enjoy happy hour and take in the fabulous views at every port! Every day the crew was helpful and positive providing details about excursions and ports. There was so much to see and a welcome ship to come back to share each day's experience."
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8 days From$4,540
Price updated 1 year+ ago
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Save this trip to your favorites or other list
River Cruise
Lodging level
Premium - 4 star
Physical level
Easy
Trip pace
Flexible schedule
Highlights
- Enjoy a warm welcome at the visitor’s center by tour guides who are eager to share their knowledge.
- Visiting one the many fine museums, to participating in a hands-on creative workshop at a local art gallery.
- Visit the studios and galleries of Paducah’s resident artists.
- See the Sailor Man's likeness in the town's own six-foot-tall bronze metal statue.
- Visit the Museum of Westward Expansion and discover the lives of the explorers, cowboys and Native Americans who helped forge our nation.
Themes
Cultural, Nature & Wildlife, National Parks
What travelers are saying
"The food and entertainment were exceptional! Such a professional staff providing top notch service! The entertainment was different each night throughout the entire trip. Also, the chef was a former Food Network Chopped Champion delivering a variety of delicious options, including desserts! Loved the cooking class for our day at sea! This is a new ship with beautiful cabins and common areas. There was plenty of space to meet with friends, enjoy happy hour and take in the fabulous views at every port! Every day the crew was helpful and positive providing details about excursions and ports. There was so much to see and a welcome ship to come back to share each day's experience."
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8 days From$3,995
Price updated 1 year+ ago
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Save this trip to your favorites or other list
River Cruise
Lodging level
Standard - 3 star
Physical level
Easy
Trip pace
Flexible schedule
Highlights
- Enjoy a show at the historic Sheldon Performing Arts Theatre or observe the beauty of nature at one of Red Wing’s 38 parks.
- Enjoy beautiful gardens, an outdoor performance center, and inspiring sculptures.
- Visit the national Mississippi River Museum and Aquarium.
- Visit the Interpretive Center, home to 15 original Normal Rockwell paintings, the Becky Hatcher House, the Huck Finn Home
- See the historic stables built in 1885 and the world-famous Clydesdale horses.
Themes
Nature & Wildlife, National Parks
What travelers are saying
"The food and entertainment were exceptional! Such a professional staff providing top notch service! The entertainment was different each night throughout the entire trip. Also, the chef was a former Food Network Chopped Champion delivering a variety of delicious options, including desserts! Loved the cooking class for our day at sea! This is a new ship with beautiful cabins and common areas. There was plenty of space to meet with friends, enjoy happy hour and take in the fabulous views at every port! Every day the crew was helpful and positive providing details about excursions and ports. There was so much to see and a welcome ship to come back to share each day's experience."
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15 days From$8,850
Price updated 1 year+ ago
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River Cruise
Lodging level
Premium - 4 star
Physical level
Easy
Trip pace
Flexible schedule
Highlights
- Visit the Museum of Westward Expansion
- Enjoy St. Louis’ many world-class attractions, including the Art Museum, Science Center, Anheuser-Busch Brewery, and the Missouri History Museum.
- See the historic stables built in 1885 and the world-famous Clydesdale horses.
- Visit the Interpretive Center, home to 15 original Normal Rockwell paintings, the Becky Hatcher House, the Huck Finn Home
- Visit the national Mississippi River Museum and Aquarium.
Themes
Cultural, Nature & Wildlife, National Parks
What travelers are saying
"The food and entertainment were exceptional! Such a professional staff providing top notch service! The entertainment was different each night throughout the entire trip. Also, the chef was a former Food Network Chopped Champion delivering a variety of delicious options, including desserts! Loved the cooking class for our day at sea! This is a new ship with beautiful cabins and common areas. There was plenty of space to meet with friends, enjoy happy hour and take in the fabulous views at every port! Every day the crew was helpful and positive providing details about excursions and ports. There was so much to see and a welcome ship to come back to share each day's experience."
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9 days From$3,995
Price updated 1 year+ ago
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Save this trip to your favorites or other list
River Cruise
Lodging level
Standard - 3 star
Physical level
Easy
Trip pace
Flexible schedule
Highlights
- Enjoying the shade of the leafy canopy greet us on arrival and are our guides for the day
- Enjoy the local flavors, like chicory coffee, sweet beignets, and famous New Orleans jazz music.
- Explore the most popular areas including the French Quarter, the colorful garden district
Themes
Cultural, Nature & Wildlife, National Parks
What travelers are saying
"The food and entertainment were exceptional! Such a professional staff providing top notch service! The entertainment was different each night throughout the entire trip. Also, the chef was a former Food Network Chopped Champion delivering a variety of delicious options, including desserts! Loved the cooking class for our day at sea! This is a new ship with beautiful cabins and common areas. There was plenty of space to meet with friends, enjoy happy hour and take in the fabulous views at every port! Every day the crew was helpful and positive providing details about excursions and ports. There was so much to see and a welcome ship to come back to share each day's experience."
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5 days From$2,285
Price updated 1 year+ ago
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Save this trip to your favorites or other list
River Cruise
Lodging level
Premium - 4 star
Physical level
Easy
Trip pace
Flexible schedule
Highlights
- Visit the picturesque Sydney and Walda Besthoff Sculpture Garden, one of the premier sculpture installations in the United States.
- Enjoy a grand tour of one of the most historic cities in the South.
- Enjoy a relaxing trip through the historic sites of the largest city in Mississippi including Cotton Row, the Mount Holly Plantation and the Weatherbee House.
- Visit iconic sites such as the National Civil Rights Museum
- Exploring this historic site,
Themes
Cultural, Nature & Wildlife, National Parks
What travelers are saying
"The food and entertainment were exceptional! Such a professional staff providing top notch service! The entertainment was different each night throughout the entire trip. Also, the chef was a former Food Network Chopped Champion delivering a variety of delicious options, including desserts! Loved the cooking class for our day at sea! This is a new ship with beautiful cabins and common areas. There was plenty of space to meet with friends, enjoy happy hour and take in the fabulous views at every port! Every day the crew was helpful and positive providing details about excursions and ports. There was so much to see and a welcome ship to come back to share each day's experience."
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22 days From$12,030
Price updated 1 year+ ago
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Save this trip to your favorites or other list
River Cruise
Lodging level
Standard - 3 star
Physical level
Easy
Trip pace
Flexible schedule
Highlights
- Enjoy a grand tour of one of the most historic and unforgettable cities in the South.
- Visit Graceland, and then tour the W.C. Handy Museum; Shelby Farms, the largest urban park in the country
- Visit iconic sites such as the National Civil Rights Museum, St. Judes Children’s Research Hospital
- Visit the Museum of Westward Expansion
- See the historic stables built in 1885 and the world-famous Clydesdale horses.
Themes
Cultural, Nature & Wildlife, National Parks
What travelers are saying
"The food and entertainment were exceptional! Such a professional staff providing top notch service! The entertainment was different each night throughout the entire trip. Also, the chef was a former Food Network Chopped Champion delivering a variety of delicious options, including desserts! Loved the cooking class for our day at sea! This is a new ship with beautiful cabins and common areas. There was plenty of space to meet with friends, enjoy happy hour and take in the fabulous views at every port! Every day the crew was helpful and positive providing details about excursions and ports. There was so much to see and a welcome ship to come back to share each day's experience."
Save this trip to your favorites or other list
11 days From$5,560
Price updated 1 year+ ago
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Save this trip to your favorites or other list
River Cruise
Lodging level
Premium - 4 star
Physical level
Easy
Trip pace
Flexible schedule
Highlights
- Enjoy the Art Museum, Science Center, Anheuser-Busch Brewery, and the Missouri History Museum.
- Enjoy shore excursions to Cape River Heritage Museum and the Red House Interpretive Center.
- Visit the studios and galleries of Paducah’s resident artists.
- Enjoy the gentle sounds of the paddlewheel as it churns through the placid waters of the Ohio River.
- Visit the Kentucky Derby Museum to see actual Derby footage dating as far back as 1918.
Themes
Cultural, Nature & Wildlife, Hiking & Walking, National Parks
What travelers are saying
"The food and entertainment were exceptional! Such a professional staff providing top notch service! The entertainment was different each night throughout the entire trip. Also, the chef was a former Food Network Chopped Champion delivering a variety of delicious options, including desserts! Loved the cooking class for our day at sea! This is a new ship with beautiful cabins and common areas. There was plenty of space to meet with friends, enjoy happy hour and take in the fabulous views at every port! Every day the crew was helpful and positive providing details about excursions and ports. There was so much to see and a welcome ship to come back to share each day's experience."
Save this trip to your favorites or other list
11 days From$5,560
Price updated 1 year+ ago
More
Plan Your Mississippi River National Parks River Cruises & Packages Trip
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All Mississippi River National Parks River Cruises & Packages, expedition cruises, self guided adventures and vacation packages. Find the best guided and expert planned vacation and holiday packages. Read more about Mississippi River National Parks River Cruises & Packages
Mississippi River National Parks River Cruises & Packages Reviews
American Cruise Line's American Jazz Doesn't Disappoint
This was our first Mississippi River Cruise. American Cruise Line was fabulous from the moment we stepped onboard. American Jazz was beautifully appointed. We so enj...
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