Top Mississippi River River Cruise Trips &amp; Packages In 2025/2026

none

5/5 Excellent

River Cruise

Lodging level

Standard - 3 star

Physical level

Easy

Trip pace

Flexible schedule

Highlights

Visit their popular gift shop which is known for their world-famous pralines.
Enjoying the shade of the leafy canopy greet us on arrival and are our guides for the day.
Visits to its gardens, historic homes, and museums
See why this show is called "Becoming Jelly Roll."
Enjoy the local flavors, like chicory coffee, sweet beignets, and famous New Orleans jazz music.

Themes

Cultural, Nature & Wildlife, National Parks

What travelers are saying

"The food and entertainment were exceptional! Such a professional staff providing top notch service! The entertainment was different each night throughout the entire trip. Also, the chef was a former Food Network Chopped Champion delivering a variety of delicious options, including desserts! Loved the cooking class for our day at sea! This is a new ship with beautiful cabins and common areas. There was plenty of space to meet with friends, enjoy happy hour and take in the fabulous views at every port! Every day the crew was helpful and positive providing details about excursions and ports. There was so much to see and a welcome ship to come back to share each day's experience."

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8 days From$4,540

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Cumberland River Cruise

none

4.5/5 Excellent

River Cruise

Lodging level

Premium - 4 star

Physical level

Easy

Trip pace

Flexible schedule

Highlights

Enjoy a warm welcome at the visitor’s center by tour guides who are eager to share their knowledge.
Visiting one the many fine museums, to participating in a hands-on creative workshop at a local art gallery.
Visit the studios and galleries of Paducah’s resident artists.
See the Sailor Man's likeness in the town's own six-foot-tall bronze metal statue.
Visit the Museum of Westward Expansion and discover the lives of the explorers, cowboys and Native Americans who helped forge our nation.

Themes

Cultural, Nature & Wildlife, National Parks

What travelers are saying

"The food and entertainment were exceptional! Such a professional staff providing top notch service! The entertainment was different each night throughout the entire trip. Also, the chef was a former Food Network Chopped Champion delivering a variety of delicious options, including desserts! Loved the cooking class for our day at sea! This is a new ship with beautiful cabins and common areas. There was plenty of space to meet with friends, enjoy happy hour and take in the fabulous views at every port! Every day the crew was helpful and positive providing details about excursions and ports. There was so much to see and a welcome ship to come back to share each day's experience."

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8 days From$3,995

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Complete Mississippi River Cruise

none

4.5/5 Excellent

River Cruise

Lodging level

Premium - 4 star

Physical level

Easy

Trip pace

Flexible schedule

Highlights

Visit the picturesque Sydney and Walda Besthoff Sculpture Garden, one of the premier sculpture installations in the United States.
Enjoy a grand tour of one of the most historic cities in the South.
Enjoy a relaxing trip through the historic sites of the largest city in Mississippi including Cotton Row, the Mount Holly Plantation and the Weatherbee House.
Visit iconic sites such as the National Civil Rights Museum
Exploring this historic site,

Themes

Cultural, Nature & Wildlife, National Parks

What travelers are saying

"The food and entertainment were exceptional! Such a professional staff providing top notch service! The entertainment was different each night throughout the entire trip. Also, the chef was a former Food Network Chopped Champion delivering a variety of delicious options, including desserts! Loved the cooking class for our day at sea! This is a new ship with beautiful cabins and common areas. There was plenty of space to meet with friends, enjoy happy hour and take in the fabulous views at every port! Every day the crew was helpful and positive providing details about excursions and ports. There was so much to see and a welcome ship to come back to share each day's experience."

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22 days From$12,030

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Ohio River Cruise

none

4.5/5 Excellent

River Cruise

Lodging level

Premium - 4 star

Physical level

Easy

Trip pace

Flexible schedule

Highlights

Enjoy the Art Museum, Science Center, Anheuser-Busch Brewery, and the Missouri History Museum.
Enjoy shore excursions to Cape River Heritage Museum and the Red House Interpretive Center.
Visit the studios and galleries of Paducah’s resident artists.
Enjoy the gentle sounds of the paddlewheel as it churns through the placid waters of the Ohio River.
Visit the Kentucky Derby Museum to see actual Derby footage dating as far back as 1918.

Themes

Cultural, Nature & Wildlife, Hiking & Walking, National Parks

What travelers are saying

"The food and entertainment were exceptional! Such a professional staff providing top notch service! The entertainment was different each night throughout the entire trip. Also, the chef was a former Food Network Chopped Champion delivering a variety of delicious options, including desserts! Loved the cooking class for our day at sea! This is a new ship with beautiful cabins and common areas. There was plenty of space to meet with friends, enjoy happy hour and take in the fabulous views at every port! Every day the crew was helpful and positive providing details about excursions and ports. There was so much to see and a welcome ship to come back to share each day's experience."

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11 days From$5,560

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Memphis - St. Louis Cruise

none

4.5/5 Excellent

River Cruise

Lodging level

Premium - 4 star

Physical level

Easy

Trip pace

Flexible schedule

Highlights

Stroll through the quaint town of New Madrid, filled with Old South traditions and historical attractions.
Discover Paducah’s colorful history during a guided tour through the town’s historic district.
Participate in hands-on creative workshops and hear artists’ stories of how they relocated to Paducah.
Hear stories of the people and events that helped shape life along the Ohio River during a guided tour of the River Heritage Museum.
Join a local guide on a narrated tour through Cape Girardeau’s beautiful Old St. Vincent’s Church.

Themes

Cultural, 50 Plus, Small Ship Cruise

What travelers are saying

"The food and entertainment were exceptional! Such a professional staff providing top notch service! The entertainment was different each night throughout the entire trip. Also, the chef was a former Food Network Chopped Champion delivering a variety of delicious options, including desserts! Loved the cooking class for our day at sea! This is a new ship with beautiful cabins and common areas. There was plenty of space to meet with friends, enjoy happy hour and take in the fabulous views at every port! Every day the crew was helpful and positive providing details about excursions and ports. There was so much to see and a welcome ship to come back to share each day's experience."

By American Queen Steamboat Company

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8 days From$4,540

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Memphis to St. Louis

none

5/5 Excellent

100+ reviews

River Cruise

Lodging level

Premium - 4 star

Physical level

Easy

Trip pace

Flexible schedule

Highlights

The family recipes of acclaimed Southern chef Regina Charboneau
The only steamboat with multiple specialty dining options, all at no additional charge
Daily lectures by the Riverlorian, our onboard historian
Professional showboat-style entertainment and dancing nightly
Our own dedicated fleet of Steamcoaches

Themes

50 Plus, Small Ship Cruise

What travelers are saying

"We had a wonderful cruise up the Mississippi from New Orleans to St Louis ! Great entertainment, great food , pools, hot tub and visiting interesting places."