Mississippi River Luxury Trips & Packages Tours & Trips

12 Mississippi River Luxury Trips & Packages trips. Tours from 6 tour companies. 1 reviews.

12 Trips match your criteria (1 - 12 shown)

Cumberland River Cruise
Save this trip to your favorites or other list
River Cruise
Lodging level
Premium - 4 star
Physical level
Easy
Trip pace
Flexible schedule

Highlights

  • Enjoy a warm welcome at the visitor’s center by tour guides who are eager to share their knowledge.
  • Visiting one the many fine museums, to participating in a hands-on creative workshop at a local art gallery.
  • Visit the studios and galleries of Paducah’s resident artists.
  • See the Sailor Man's likeness in the town's own six-foot-tall bronze metal statue.
  • Visit the Museum of Westward Expansion and discover the lives of the explorers, cowboys and Native Americans who helped forge our nation.

Themes

Cultural, Nature & Wildlife, National Parks

What travelers are saying

"The food and entertainment were exceptional! Such a professional staff providing top notch service! The entertainment was different each night throughout the entire trip. Also, the chef was a former Food Network Chopped Champion delivering a variety of delicious options, including desserts! Loved the cooking class for our day at sea! This is a new ship with beautiful cabins and common areas. There was plenty of space to meet with friends, enjoy happy hour and take in the fabulous views at every port! Every day the crew was helpful and positive providing details about excursions and ports. There was so much to see and a welcome ship to come back to share each day's experience."

Trip dates & details
Save this trip to your favorites or other list
More
Upper Mississippi River Cruise
Save this trip to your favorites or other list
River Cruise
Lodging level
Premium - 4 star
Physical level
Easy
Trip pace
Flexible schedule

Highlights

  • Visit the Museum of Westward Expansion
  • Enjoy St. Louis’ many world-class attractions, including the Art Museum, Science Center, Anheuser-Busch Brewery, and the Missouri History Museum.
  • See the historic stables built in 1885 and the world-famous Clydesdale horses.
  • Visit the Interpretive Center, home to 15 original Normal Rockwell paintings, the Becky Hatcher House, the Huck Finn Home
  • Visit the national Mississippi River Museum and Aquarium.

Themes

Cultural, Nature & Wildlife, National Parks

What travelers are saying

"The food and entertainment were exceptional! Such a professional staff providing top notch service! The entertainment was different each night throughout the entire trip. Also, the chef was a former Food Network Chopped Champion delivering a variety of delicious options, including desserts! Loved the cooking class for our day at sea! This is a new ship with beautiful cabins and common areas. There was plenty of space to meet with friends, enjoy happy hour and take in the fabulous views at every port! Every day the crew was helpful and positive providing details about excursions and ports. There was so much to see and a welcome ship to come back to share each day's experience."

Trip dates & details
Save this trip to your favorites or other list
More
Complete Mississippi River Cruise
Save this trip to your favorites or other list
River Cruise
Lodging level
Premium - 4 star
Physical level
Easy
Trip pace
Flexible schedule

Highlights

  • Visit the picturesque Sydney and Walda Besthoff Sculpture Garden, one of the premier sculpture installations in the United States.
  • Enjoy a grand tour of one of the most historic cities in the South.
  • Enjoy a relaxing trip through the historic sites of the largest city in Mississippi including Cotton Row, the Mount Holly Plantation and the Weatherbee House.
  • Visit iconic sites such as the National Civil Rights Museum
  • Exploring this historic site,
Show more

Themes

Cultural, Nature & Wildlife, National Parks

What travelers are saying

"The food and entertainment were exceptional! Such a professional staff providing top notch service! The entertainment was different each night throughout the entire trip. Also, the chef was a former Food Network Chopped Champion delivering a variety of delicious options, including desserts! Loved the cooking class for our day at sea! This is a new ship with beautiful cabins and common areas. There was plenty of space to meet with friends, enjoy happy hour and take in the fabulous views at every port! Every day the crew was helpful and positive providing details about excursions and ports. There was so much to see and a welcome ship to come back to share each day's experience."

Trip dates & details
Save this trip to your favorites or other list
More
Custom Designed Trip
Lodging level
lodgingLevelName
Physical level
N/A

Highlights

  • Fully customized trip based on preferences
  • Matched with a local specialist
  • From $200 per person per day
Self-Guided / Independent Tour
Ohio River Cruise
Save this trip to your favorites or other list
River Cruise
Lodging level
Premium - 4 star
Physical level
Easy
Trip pace
Flexible schedule

Highlights

  • Enjoy the Art Museum, Science Center, Anheuser-Busch Brewery, and the Missouri History Museum.
  • Enjoy shore excursions to Cape River Heritage Museum and the Red House Interpretive Center.
  • Visit the studios and galleries of Paducah’s resident artists.
  • Enjoy the gentle sounds of the paddlewheel as it churns through the placid waters of the Ohio River.
  • Visit the Kentucky Derby Museum to see actual Derby footage dating as far back as 1918.
Show more

Themes

Cultural, Nature & Wildlife, Hiking & Walking, National Parks

What travelers are saying

"The food and entertainment were exceptional! Such a professional staff providing top notch service! The entertainment was different each night throughout the entire trip. Also, the chef was a former Food Network Chopped Champion delivering a variety of delicious options, including desserts! Loved the cooking class for our day at sea! This is a new ship with beautiful cabins and common areas. There was plenty of space to meet with friends, enjoy happy hour and take in the fabulous views at every port! Every day the crew was helpful and positive providing details about excursions and ports. There was so much to see and a welcome ship to come back to share each day's experience."

Trip dates & details
Save this trip to your favorites or other list
More
Memphis - St. Louis Cruise
Save this trip to your favorites or other list
River Cruise
Lodging level
Premium - 4 star
Physical level
Easy
Trip pace
Flexible schedule

Highlights

  • Stroll through the quaint town of New Madrid, filled with Old South traditions and historical attractions.
  • Discover Paducah’s colorful history during a guided tour through the town’s historic district.
  • Participate in hands-on creative workshops and hear artists’ stories of how they relocated to Paducah.
  • Hear stories of the people and events that helped shape life along the Ohio River during a guided tour of the River Heritage Museum.
  • Join a local guide on a narrated tour through Cape Girardeau’s beautiful Old St. Vincent’s Church.
Show more

Themes

Cultural, 50 Plus, Small Ship Cruise

What travelers are saying

"The food and entertainment were exceptional! Such a professional staff providing top notch service! The entertainment was different each night throughout the entire trip. Also, the chef was a former Food Network Chopped Champion delivering a variety of delicious options, including desserts! Loved the cooking class for our day at sea! This is a new ship with beautiful cabins and common areas. There was plenty of space to meet with friends, enjoy happy hour and take in the fabulous views at every port! Every day the crew was helpful and positive providing details about excursions and ports. There was so much to see and a welcome ship to come back to share each day's experience."

Trip dates & details
Save this trip to your favorites or other list
More
Memphis to St. Louis
Save this trip to your favorites or other list
River Cruise
Lodging level
Premium - 4 star
Physical level
Easy
Trip pace
Flexible schedule

Highlights

  • The family recipes of acclaimed Southern chef Regina Charboneau
  • The only steamboat with multiple specialty dining options, all at no additional charge
  • Daily lectures by the Riverlorian, our onboard historian
  • Professional showboat-style entertainment and dancing nightly
  • Our own dedicated fleet of Steamcoaches
Show more

Themes

50 Plus, Small Ship Cruise

What travelers are saying

"We had a wonderful cruise up the Mississippi from New Orleans to St Louis ! Great entertainment, great food , pools, hot tub and visiting interesting places."

Trip dates & details
Save this trip to your favorites or other list
More

Unlock Community Benefits

Travel better together

  • Save favorite trips and itineraries
  • Get insider insights
  • Receive personalized recommendations
  • ... and much more
Join community
Music of America: Nashville to New Orleans 2025
Save this trip to your favorites or other list
Small Group Tour
Lodging level
Premium - 4 star
Physical level
Moderate

Visits

Memphis, Nashville

Highlights

  • The sounds of the South come to life on a 9-day journey from 'Music City' Nashville to 'The Big Easy' New Orleans
  • the birthplace of jazz...Discover the birthplaces of some of the world's most famous genres... rock n' roll
  • blues
  • jazz
  • country... on an exploration across the south that provides insight into their creation and the innovators that helped push them to the forefront of the music world. Stroll the halls of the Country Music Hall of Fame and Museum
Show more

Themes

Cultural

What travelers are saying

"My husband and I booked the Yellowstone tour with Tauck expecting so much more with the accommodations, food, and tour director based on the price point. We were sadly disappointed but still tried to enjoy the experience. Rooms were dirty, food were often buffets and other group dinners with some food inedible. We noticed other tours staying in our hotels and paying much less for their tours. One positive was we never touched our luggage which was nice but my small suitcase was damaged during one transfer. Word to the wise… read their emails thoroughly as the email we received a few weeks before our trip reads like a disclaimer for poor service and accommodations."

Trip dates & details
Save this trip to your favorites or other list
More
Soul of the Mississippi
Save this trip to your favorites or other list
Small Ship Cruise
Lodging level
Premium - 4 star
Physical level
Easy
Trip pace
Flexible schedule

Highlights

  • Discover Memphis
  • See one of the oldest Protestant churches in Louisiana
  • Explore New Orleans
  • Visit Oak Alley Plantation and St. Francisville

Themes

Cultural, Nature & Wildlife, National Parks, Small Ship Cruise

What travelers are saying

"Amazing tours,prepared and extremely helpful guides. Great experience overall.Highly recommended."

Trip dates & details
Save this trip to your favorites or other list
More
Travelstride Gift Card
One card, thousands of extraordinary trips
Gifts Card

Mississippi River Luxury Trips & Packages Reviews

R

Robyn

Jan 2017

What a holiday!

I was lucky enough to have 7 wonderful nights on the American Queen ... Along with 17 of my friends and family... From Memphis to New Orleans..Wow !! ... Cannot spea...

Write a Review

Always Find the Best

On Travelstride you can find 12 trips to Mississippi River Luxury Trips & Packages and more than 20,000 trips worldwide ranging from budget to luxury and private guided to group tours and everything in between. Only on Stride can you find and compare expert-planned trips from 1,000+ tour operators, cruise lines and local experts. Read traveler and professional reviews so you can confidently find your perfect trip.

Top Tour Companies on Travelstride:
All 1,600+ companies >
Sign in to reveal savings up to $700 per person!